<scp>d</scp> ‐Dimer Level After Endovascular Treatment Can Help Predict Outcome of Acute Ischemic Stroke

Background d ‐Dimer level is a marker of hypercoagulability, which associated with thrombus formation and resolution. We investigated the value ‐dimer levels in predicting outcomes acute ischemic stroke patients who underwent endovascular treatment (EVT). Methods analyzed data only EVT from SECRET (Selection Criteria Endovascular Thrombectomy Thrombolytic Therapy) registry. were routinely measured 10 15 participating hospitals. Patients grouped into tertiles (tertile 1, tertile 2, 3) according to (lowest, moderate, highest, respectively). compared serial scores on National Institutes Health Stroke Scale at baseline, day 1 hospitalization, discharge; functional outcome 3 months after EVT; rate mortality within 6 EVT. Results In 170 patients, median was 477 ng/mL (interquartile range, 249–988 ng/mL). 3, score higher discharge than hospitalization. Poor (modified Rankin score, ≥3) more common high (26.3% 57.1% 76.4% 3; P &lt;0.001). Multivariable analysis showed that independently poor (odds ratio [OR], 4.399 [95% CI, 1.594–12.135]). Kaplan–Meier survival death (OR, 5.441 1.560–18.978]; log‐rank test, The effect no heterogeneity across subgroups for or direction unfavorable all demographic strata. Conclusions High plasma predictive early neurologic worsening, EVT, Registration URL: http://www.clinicaltrials.gov ; Unique identifier: NCT02964052.